Patient-Specific Dose

Dose By Weight

Medications can be a patient-specific dose, notably based on the patient’s weight. This can be very beneficial when dosing a child, or an adult with abnormal weight. Since we commonly use pounds and ounces to describe a person’s weight in the United States, we will first have to convert patient weight to kilograms. Remember there are 16 ounces in a pound and 2.2 pounds in a kilogram. See other unit conversions.

Patient-Specific Dose Example

Milly weighs 105 pounds. She is prescribed a drug with dosing of 0.8mg/2kg. What dose in milligrams should Milly be given?

Patient-speciifc dose
Set Up Dose By Weight

As you can see, the denominators’ measurement units do not match so we have to convert kilograms to pounds before we can cross-multiply. If needed, review setting up ratios and proportions.

Convert Kilograms to Pounds

For every kilogram, there are 2.2lbs so we will multiply 2 by 2.2 to the medication’s converted measurement.

2 * 2.2 = 4.4lbs

Weight converted to kilograms
Convert Kilograms to Pounds

4.4x = 0.8 * 105

4.4x = 84

x = 19.1mg

Based on this patient-specific dosing, Milly’s dose is 19.1mg.

Concentrated Dosing

Patient-specific dosing by weight can also be applied to concentrated medications as well. Consider the above example is available as a 100mg/5mL concentrated solution. What would Milly’s dose be per milliliter? We already have her dose needed per milligram from the previous example.

Determine Patient-Specific Dose of Concentrated Drug

100x = 95.5

x = 0.96mL

If Milly is given a dose from the concentrated solution, her dose is slightly less than 1mL. She will be given 0.96mL per dose.